Fatigue in Adults with Type 2 Diabetes: A Systematic Review and Meta-analysis

West J Nurs Res. 2021 Feb;43(2):172-181. doi: 10.1177/0193945920938636. Epub 2020 Jul 5.

Abstract

This review aimed to evaluate the level of fatigue in adults with type 2 diabetes measured by the validated Diabetes Symptom Checklist (DSC)and related factors. Ten studies were included. Both DSC (n = 4) and the revised (n = 6) have been used to measure fatigue. When the latter was used (n = 1082), the pooled level of fatigue was 1.77 (on a 0-5 scale). When the former was used (n = 674), the pooled level of fatigue was 1.73 (on a 0-10 scale). Participant demographics (e.g., gender), health information (e.g., BMI), and diabetes-specific factors (e.g., A1C and diabetes distress) were associated with fatigue. Fatigue was negatively related to self-care behaviors. The prevalence of significant fatigue remains unclear due to a lack of a cut-off point of the instrument. Future research is warranted to identify the threshold for clinically significant fatigue and investigate the causal relationship. Nurses are recommended to perform a routine assessment of fatigue.

Keywords: fatigue; literature review; nursing; observational; quantitative; type 2 diabetes.

Publication types

  • Meta-Analysis
  • Systematic Review

MeSH terms

  • Blood Glucose / metabolism*
  • Checklist
  • Diabetes Mellitus, Type 2 / blood
  • Diabetes Mellitus, Type 2 / epidemiology*
  • Diabetes Mellitus, Type 2 / physiopathology
  • Disease Management*
  • Fatigue* / epidemiology
  • Fatigue* / etiology
  • Humans
  • Prevalence
  • Self Care*
  • Stress, Physiological

Substances

  • Blood Glucose