Recent advances of gold nanoparticles as biomaterial in dentistry

Int J Pharm. 2020 Aug 30:586:119596. doi: 10.1016/j.ijpharm.2020.119596. Epub 2020 Jul 2.

Abstract

Major goal of dental treatment is to eradicate the existing diseases of the oral cavity and implement preventive measures to control the spread of the diseases. Various interventions are being used to cure the dental diseases. Due to the nanostructures, high surface volume and biocompatibility, Gold nanoparticles (GNPs) have been experimented in the treatment of gum diseases, dental caries, tissue engineering, dental implantology and diagnosis of cancers. GNPs possess antifungal and antibacterial activity, hence are incorporated in various biomaterials to potentiate the effect. They also enhance the mechanical properties of materials leading to improved outcomes. They are available in different sizes and concentrations to exhibits its beneficial outcomes. These properties of GNPs make these materials as choice of fillers in biomaterials. This review aims to discuss the effect of incorporation of GNPs in several biomaterials used for dental and medical applications.

Keywords: Biomaterials; Cancer; Dental implants; Dentistry; Gold nanoparticles; Tissue engineering.

Publication types

  • Review

MeSH terms

  • Biocompatible Materials
  • Dental Caries* / prevention & control
  • Dentistry
  • Gold
  • Humans
  • Metal Nanoparticles*

Substances

  • Biocompatible Materials
  • Gold