Viral Hepatitis Other than A, B, and C: Evaluation and Management

Clin Liver Dis. 2020 Aug;24(3):405-419. doi: 10.1016/j.cld.2020.04.008. Epub 2020 Apr 13.

Abstract

Viral hepatitis can cause a wide spectrum of clinical presentations from a benign form with minimal or no symptoms to acute liver failure or death. Hepatitis D coinfection and superinfection have distinct clinical courses, with the latter more likely leading to chronic infection. Management of chronic hepatitis D virus is individualized because of the paucity of treatment options and significant side effect profile of currently available treatments. Sporadic cases of hepatitis E caused by contaminated meats are becoming increasingly prevalent in immunocompromised hosts. Human herpesviruses are an important cause of disease also in immunocompromised individuals.

Keywords: Hepatitis D; Hepatitis E; Hepatotropic viruses; Human herpesvirus; Viral hepatitis.

Publication types

  • Review

MeSH terms

  • Coinfection / diagnosis
  • Cytomegalovirus Infections / complications
  • Epstein-Barr Virus Infections / complications
  • Hepatitis B / complications
  • Hepatitis D / complications
  • Hepatitis D / diagnosis*
  • Hepatitis D / drug therapy*
  • Hepatitis E / diagnosis*
  • Hepatitis E / therapy
  • Herpes Simplex / complications
  • Humans
  • Immunocompromised Host
  • Liver Diseases / virology
  • Risk Factors
  • Varicella Zoster Virus Infection / complications