Clostridium difficile disease in solid organ transplant recipients: a recommended treatment paradigm

Abstract

Purpose of review: Organ transplant recipients have an increased incidence of Clostridium difficile disease and lower clinical response rates compared with the general population. Transplant specific treatment approaches are not defined. Therefore, a review of therapeutics in the transplant population is needed.

Recent findings: A literature review on the current therapies for C. difficile was performed focusing on the evidence in transplant recipients and immunosuppressed populations.

Summary: Transplant patients warrant an aggressive approach to treatment. The authors propose a suggested treatment paradigm for therapy.