Abstract
Patients with HLA-B27 positive ankylosing spondylitis (AS) in a Swiss family study developed non-granulomatous acute anterior uveitis (AAU) 11 times more often than their healthy relatives sharing the same HLA-B27 positive haplotype (4.4% versus 0.4%; p less than 0.01) during a period of 6 months.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Acute Disease
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Adolescent
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Adult
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HLA Antigens / analysis*
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HLA Antigens / genetics
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HLA-B27 Antigen
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Haplotypes
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Humans
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Middle Aged
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Spondylitis, Ankylosing / complications*
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Spondylitis, Ankylosing / genetics
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Spondylitis, Ankylosing / immunology
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Uveitis, Anterior / complications*
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Uveitis, Anterior / genetics
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Uveitis, Anterior / immunology
Substances
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HLA Antigens
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HLA-B27 Antigen