Reply to Comment on "Association Between DCC Polymorphisms and Susceptibility to Autism Spectrum Disorder"

J Autism Dev Disord. 2020 Oct;50(10):3811-3812. doi: 10.1007/s10803-020-04585-2.

Abstract

The comments from Dr. Meisami about our article "Association between DCC polymorphisms and Susceptibility to Autism Spectrum Disorder", and we wish to respond to several points. First, 100% of detection rate for each SNP genotype cannot be obtained. Second, we listed the detection rates in Supplemental Table 1. Last, Dr. Meisami referred an article focused on two SNPs; however, our article focused on seven SNPs. If we marked the number of detected cases, we had to make a table for each result, occupying a large part of the layout. Moreover, if the number of detected cases was marked respectively, it was not in accordance with academic norms. For these reasons, we provided the actual number of cases in Table 3.

Keywords: Comment; Reason; Respond.

Publication types

  • Letter

MeSH terms

  • Autism Spectrum Disorder / diagnosis
  • Autism Spectrum Disorder / ethnology
  • Autism Spectrum Disorder / genetics*
  • DCC Receptor / genetics*
  • Female
  • Genetic Predisposition to Disease / ethnology
  • Genetic Predisposition to Disease / genetics*
  • Genotype
  • Humans
  • Male
  • Polymorphism, Single Nucleotide / genetics*

Substances

  • DCC Receptor
  • DCC protein, human