Estimating and abstracting the 3D structure of feline bones using neural networks on X-ray (2D) images

Commun Biol. 2020 Jun 30;3(1):337. doi: 10.1038/s42003-020-1057-3.

Abstract

Computing 3D bone models using traditional Computed Tomography (CT) requires a high-radiation dose, cost and time. We present a fully automated, domain-agnostic method for estimating the 3D structure of a bone from a pair of 2D X-ray images. Our triplet loss-trained neural network extracts a 128-dimensional embedding of the 2D X-ray images. A classifier then finds the most closely matching 3D bone shape from a predefined set of shapes. Our predictions have an average root mean square (RMS) distance of 1.08 mm between the predicted and true shapes, making our approach more accurate than the average achieved by eight other examined 3D bone reconstruction approaches. Each embedding extracted from a 2D bone image is optimized to uniquely identify the 3D bone CT from which the 2D image originated and can serve as a kind of fingerprint of each bone; possible applications include faster, image content-based bone database searches for forensic purposes.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Bone and Bones / anatomy & histology*
  • Bone and Bones / diagnostic imaging
  • Cats
  • Datasets as Topic
  • Femur / anatomy & histology
  • Femur / diagnostic imaging
  • Image Processing, Computer-Assisted / methods
  • Imaging, Three-Dimensional / methods
  • Models, Theoretical
  • Neural Networks, Computer
  • Radiography
  • Tomography, X-Ray Computed / methods
  • X-Rays