Increased expression of dermal LL37 may trigger migration of CCR7+ regulatory T cells in extramammary Paget's disease

J Dermatol Sci. 2020 Jul;99(1):65-68. doi: 10.1016/j.jdermsci.2020.05.003. Epub 2020 May 17.
No abstract available

Publication types

  • Letter

MeSH terms

  • Aged
  • Aged, 80 and over
  • Antimicrobial Cationic Peptides / metabolism*
  • Cathelicidins
  • Cell Movement / immunology
  • Female
  • Humans
  • Male
  • Middle Aged
  • Neoplasm Invasiveness / immunology
  • Paget Disease, Extramammary / immunology*
  • Paget Disease, Extramammary / pathology
  • Receptors, CCR7 / metabolism
  • Skin / pathology*
  • Skin Neoplasms / immunology*
  • Skin Neoplasms / pathology
  • T-Lymphocytes, Regulatory / immunology*
  • T-Lymphocytes, Regulatory / metabolism
  • Tumor Microenvironment / immunology

Substances

  • Antimicrobial Cationic Peptides
  • CCR7 protein, human
  • Receptors, CCR7
  • Cathelicidins