Oil crop genetic modification for producing added value lipids

Crit Rev Biotechnol. 2020 Sep;40(6):777-786. doi: 10.1080/07388551.2020.1785384. Epub 2020 Jun 30.

Abstract

Plant lipids, mainly stored in seeds and other plant parts, are not only a crucial resource for food and fodder but are also a promising alternative to fossil oils as a chemical industry feedstock. Oil crop cultivation and processing are always important parts of agriculture worldwide. Vegetable oils containing polyunsaturated fatty acids, very long chain fatty acids, conjugated fatty acids, hydroxy fatty acids and wax esters, have outstanding nutritional, lubricating, surfactant, and artificial-fibre-synthesis properties, amongst others. Enhancing the production of such specific lipid components is of economic interest. There has been a considerable amount of information reported about plant lipid biosynthesis, including identification of the pathway map of carbon flux, key enzymes (and the coding genes), and substrate affinities. Plant lipid biosynthesis engineering to produce special oil compounds has become feasible, although until now, only limited progress has been made in the laboratory. It is relatively easy to achieve the experimental objectives, for example, accumulating novel lipid compounds in given plant tissues facilitated by genetic modification. Applying such technologies to agricultural production is difficult, and the challenge is to make engineered crops economically attractive, which is impeded by only moderate success. To achieve this goal, more complicated and systematic strategies should be developed and discussed based on the relevant results currently available.

Keywords: Plant lipid biosynthesis; conjugated fatty acids; hydroxy fatty acids; metabolism engineering; polyunsaturated fatty acids; very long chain fatty acids; wax ester.

Publication types

  • Review

MeSH terms

  • Crops, Agricultural* / genetics
  • Crops, Agricultural* / metabolism
  • Fatty Acids* / chemistry
  • Fatty Acids* / metabolism
  • Gene Editing / methods*
  • Plant Oils* / chemistry
  • Plant Oils* / metabolism
  • Plants, Genetically Modified* / genetics
  • Plants, Genetically Modified* / metabolism
  • Seeds / genetics
  • Seeds / metabolism

Substances

  • Fatty Acids
  • Plant Oils