Infection of Ruminants, Including Pregnant Cattle, with Bungowannah Virus

Viruses. 2020 Jun 26;12(6):690. doi: 10.3390/v12060690.

Abstract

Bungowannah virus is a pestivirus known to cause reproductive losses in pigs. The virus has not been found in other species, nor is it known if it has the capacity to cause disease in other animals. Eight sheep, eight calves and seven pregnant cows were experimentally infected with Bungowannah virus. It was found that sheep and calves could be infected. Furthermore, it was shown that the virus is able to cross the bovine placenta and cause infection of the foetus. These findings demonstrate the potential for species other than pigs to become infected with Bungowannah virus and the need to prevent them from becoming infected.

Keywords: Bungowannah virus; pestivirus F; ruminant infection.

MeSH terms

  • Animals
  • Cattle
  • Cattle Diseases / virology
  • Female
  • Fetus / virology*
  • Maternal-Fetal Exchange / physiology*
  • Pestivirus / pathogenicity*
  • Pestivirus Infections / transmission*
  • Pestivirus Infections / veterinary*
  • Placenta / metabolism
  • Placenta / virology
  • Pregnancy
  • Sheep
  • Sheep Diseases / virology
  • Species Specificity
  • Swine
  • Swine Diseases / virology