Stress and Drug Use from Prepregnancy, During Pregnancy, to Postpartum

J Racial Ethn Health Disparities. 2021 Apr;8(2):454-462. doi: 10.1007/s40615-020-00802-x. Epub 2020 Jun 27.

Abstract

Objective: To document changes of stress and illicit drug use among women from 4 months prepregnancy to 6 months postpartum.

Study design: In a longitudinal study of drug use in family planning clinics, 121 women who became pregnant were matched with 202 women who did not become pregnant. Self-reported drug use, Cohen's Perceived Stress Scale, and open-ended stress questions were examined every 2 months during the study period of time.

Results: Among drug-using pregnant women, drug use declined during 2nd and 3rd trimesters and increased immediately within 1 to 2 months postpartum. Levels of perceived stress declined throughout pregnancy up to 2 months postpartum, increased at 3 to 4 months postpartum and then declined at 6 months postpartum. In contrast, among nondrug-using pregnant women, stress remained stable until the 2nd trimester, increased from 3rd trimester to 1-2 months postpartum, then declined continuously to 6 months postpartum. For non-pregnant women, at the matched timeline, there was no clear pattern for changes of drug use and stress.

Conclusions: Our study has illustrated a complex time course of changes of both perceived stress and drug use from prepregnancy through 6 months postpartum. For drug-using pregnant women, pregnancy showed protective effect in reduction of both drug use and stress during pregnancy; and during postpartum, drug resumption peaked at 1-2 months while stress peaked at 3-4 months. If we can identify modifiable, pregnancy-related resiliency factors for both stress and drug use, we can begin to extend prevention efforts initiated during pregnancy into the postpartum period.

Keywords: Drug use; Postpartum; Pregnancy; Prepregnancy; Stress.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Adolescent
  • Adult
  • Female
  • Humans
  • Longitudinal Studies
  • Peripartum Period
  • Postpartum Period
  • Pregnancy
  • Pregnant Women / psychology*
  • Stress, Psychological / epidemiology*
  • Substance-Related Disorders / epidemiology*
  • Young Adult