Guillain-Barré syndrome in a patient infected with SARS-CoV-2, a case report

Mohammad Amin Farzi; Hormoz Ayromlou; Naser Jahanbakhsh; Parisa Hadavi Bavil; Abdolali Janzadeh; Farid Karkon Shayan

doi:10.1016/j.jneuroim.2020.577294

Guillain-Barré syndrome in a patient infected with SARS-CoV-2, a case report

J Neuroimmunol. 2020 Jun 20:346:577294. doi: 10.1016/j.jneuroim.2020.577294. Online ahead of print.

Authors

Mohammad Amin Farzi¹, Hormoz Ayromlou², Naser Jahanbakhsh³, Parisa Hadavi Bavil³, Abdolali Janzadeh², Farid Karkon Shayan²

Affiliations

¹ Tabriz University of Medical Sciences, Iran. Electronic address: farzi.neuro@gmail.com.
² Tabriz University of Medical Sciences, Iran.
³ Urmia University of Medical Sciences, Iran.

Abstract

Background: The COVID-19 is a novel condition affecting all the world, so every manifestation of disease should be reported. Neurologic manifestations of the disease are increasingly identified and this will help clinician to improve their diagnostic and therapeutic skills in dealing with COVID-19 patients.

Case: In this article we report a 41-year-old male that developed ascending paresthesia and paralysis following infection with SARS-CoV-2 virus. Electrodiagnostic evaluation in patient revealed demyelinating type polyneuropathy and patient diagnosed as Guillain-Barré syndrome (AIDP type) and treated with IVIG which resulted in favorable response.

Conclusions: Considering this report and other reports that are mentioned in our short review, there is probably causal relationship between COVID-19 and development of Guillain-Barré syndrome.

Keywords: COVID-19; Guillain-Barré syndrome; SARS-CoV-2.