Treating Dyslipidemias in the Primary Prevention of Atherosclerotic Cardiovascular Disease in Older Adults with Diabetes Mellitus

Clin Geriatr Med. 2020 Aug;36(3):457-476. doi: 10.1016/j.cger.2020.04.006. Epub 2020 Apr 17.

Abstract

People with diabetes mellitus (DM), especially those who are older, are at higher risk for premature morbidity and mortality related to atherosclerotic cardiovascular disease (ASCVD). Clinical practice guidelines recommend statin therapy for people with DM ages 40 to 75 years. The evidence for those greater than 75 years of age is relatively limited at present. Other health problems should be considered when planning ASCVD primary prevention in adults ages greater than 75 years with DM. Clinicians should discuss the risks and benefits of each plan with these patients and their caregivers.

Keywords: Cardiovascular disease; Dyslipidemias; Older people with diabetes; Primary prevention.

Publication types

  • Review

MeSH terms

  • Aged
  • Atherosclerosis / etiology
  • Atherosclerosis / prevention & control*
  • Cardiovascular Diseases / etiology
  • Cardiovascular Diseases / prevention & control*
  • Diabetes Mellitus, Type 2 / complications*
  • Dyslipidemias / drug therapy*
  • Female
  • Humans
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors / adverse effects
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors / therapeutic use*
  • Male
  • Primary Prevention*
  • Risk Factors

Substances

  • Hydroxymethylglutaryl-CoA Reductase Inhibitors