Assessment of the Role of Vitamin D in the Treatment of Oral Lichen Planus

J Contemp Dent Pract. 2020 Apr 1;21(4):390-395.

Abstract

Aim: Lichen planus is an autoimmune disease that can affect the skin and mucous membranes, including the oral mucosa. Vitamin D plays a very important role in the bone health along with boosting immunity. This study was carried out to assess the role of vitamin D in the treatment of oral lichen planus.

Materials and methods: A sample size of 450 was taken which included patients showing clinical presentation of oral lichen planus. The patients were equally divided into three different groups based on their vitamin D levels. The data were analyzed using SPSS version 26.0.

Results: The patients who were given the vitamin D supplementation showed the maximum improvement. The comparison of the data were found to be statistically significant.

Conclusion: It was concluded that vitamin D played an important role in the treatment of oral lichen planus.

Clinical significance: The role of vitamin D in lichen planus needs to be explored. This study may be useful in conducting further study to assess the role in vitamin D supplementation in the treatment of oral lichen planus.

Keywords: Autoimmune disorder; Oral lichen planus Vitamin D..

MeSH terms

  • Humans
  • Lichen Planus*
  • Lichen Planus, Oral*
  • Mouth Mucosa
  • Skin
  • Vitamin D

Substances

  • Vitamin D