Stopping Clinical Trials in Inflammatory Bowel Disease During the COVID-19 Pandemic Is Not a Responsible Act

J Crohns Colitis. 2020 Dec 2;14(12):1765-1768. doi: 10.1093/ecco-jcc/jjaa127.

Abstract

The intense competition for resources to combat COVID-19 has greatly reduced access to health care for patients with other diseases. After the disastrous overrun of hospitals through COVID-19 patients in some jurisdictions, availability of resources for 'elective' medical procedures, including care for the chronically ill, has been greatly reduced in many places as a pre-emptive measure before or during the blooming of infection clusters. Pharmaceutical companies have either stopped recruitment or even cancelled ongoing clinical trials in chronic diseases. Pre-emptive triage and its impact on medical ethics is discussed in the framework of care for inflammatory bowel disease.

Keywords: Crohn disease; drug development; ethics; registration trial; regulatory trials; ulcerative colitis.

MeSH terms

  • Anti-Inflammatory Agents / therapeutic use*
  • COVID-19 / epidemiology
  • COVID-19 / prevention & control*
  • Chronic Disease
  • Clinical Trials as Topic / ethics*
  • Drug Development / ethics*
  • Global Health
  • Health Care Rationing / ethics*
  • Health Services Accessibility / ethics*
  • Humans
  • Inflammatory Bowel Diseases / drug therapy*
  • Pandemics / prevention & control
  • Triage / ethics
  • Triage / methods

Substances

  • Anti-Inflammatory Agents