Effect of sagittal shape on proximal junctional kyphosis following thoracopelvic corrective fusion for adult spinal deformity: postoperative inflection vertebra cranial to T12 is a significant risk factor

Spine Deform. 2020 Dec;8(6):1313-1323. doi: 10.1007/s43390-020-00162-w. Epub 2020 Jun 23.

Abstract

Study design: This was a retrospective analysis of a prospectively collected consecutive case series of patients with adult spinal deformity (ASD).

Objective: This study aimed to investigate the impact of the geometrical sagittal shape of the corrected spine on the development of proximal junctional kyphosis (PJK). Several studies have documented risk factors for PJK in ASD surgery. Geometrical assessment is vital for evaluating sagittal spinal deformity. It is essential to assess the postoperative geometrical shape of the spine and the location of the correction in the spine to decrease postoperative junctional stress and PJK.

Methods: Consecutive patients with ASD who underwent corrective fusion with long constructs to the pelvis were included. Patients with neuromuscular disease, congenital and adolescent scoliosis, infection, and spinal tumor were excluded. We investigated the spinopelvic and geometrical parameters of the whole spine. The locations of the thoracic and lumbar apical vertebrae and the inflection vertebrae (IV), where the curvature of the associated adjacent vertebral bodies changes from kyphosis to lordosis, were investigated. The subjects were divided into PJK included patients who underwent revision surgery for junctional failure or with a change in proximal junctional angle ≥ 20°, and non-PJK groups.

Results: A total of 139 patients (mean age, 69.6 years; range 18-82 years) were included. There were 47 and 92 patients in the PJK and non-PJK groups, respectively. The IV were located significantly cranial and posterior, the lumbar apex were located significantly posterior in the PJK group at the immediate postoperative time points. The significant risk factors for PJK on binary logistic regression were cranial IV and posterior lumbar apical vertebrae. The incidence of PJK in patients with IV at T12 or cranial tends PJK significantly higher (69%) than at L1 or caudal (26%).

Conclusions: Geometrical spinal shape should be taken into account to reduce the rate of postoperative mechanical complications.

Level of evidence: Level of evidence III.

Keywords: Adult spinal deformity; Corrective fusion surgery; Mechanical complication; Proximal junctional kyphosis; Spinal geometry.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Female
  • Humans
  • Kyphosis / etiology*
  • Kyphosis / pathology
  • Lumbar Vertebrae / pathology*
  • Male
  • Middle Aged
  • Pelvis / surgery*
  • Postoperative Complications / etiology*
  • Postoperative Complications / pathology
  • Retrospective Studies
  • Risk Factors
  • Spinal Curvatures / surgery*
  • Spinal Fusion / adverse effects*
  • Spinal Fusion / methods*
  • Stress, Mechanical
  • Thoracic Vertebrae / pathology*
  • Thoracic Vertebrae / surgery*
  • Young Adult