Constitutive modeling of menisci tissue: a critical review of analytical and numerical approaches

Biomech Model Mechanobiol. 2020 Dec;19(6):1979-1996. doi: 10.1007/s10237-020-01352-1. Epub 2020 Jun 22.

Abstract

Menisci are fibrocartilaginous disks consisting of soft tissue with a complex biomechanical structure. They are critical determinants of the kinematics as well as the stability of the knee joint. Several studies have been carried out to formulate tissue mechanical behavior, leading to the development of a wide spectrum of constitutive laws. In addition to developing analytical tools, extensive numerical studies have been conducted on menisci modeling. This study reviews the developments of the most widely used continuum models of the meniscus mechanical properties in conjunction with emerging analytical and numerical models used to study the meniscus. The review presents relevant approaches and assumptions used to develop the models and includes discussions regarding strengths, weaknesses, and discrepancies involved in the presented models. The study presents a comprehensive coverage of relevant publications included in Compendex, EMBASE, MEDLINE, PubMed, ScienceDirect, Springer, and Scopus databases. This review aims at opening novel avenues for improving menisci modeling within the framework of constitutive modeling through highlighting the needs for further research directed toward determining key factors in gaining insight into the biomechanics of menisci which is crucial for the elaborate design of meniscal replacements.

Keywords: Analytical and numerical models; Constitutive modeling; Literature review; Mechanical properties; Menisci; Whole knee models.

Publication types

  • Review

MeSH terms

  • Animals
  • Anisotropy
  • Arthroplasty, Replacement, Knee / methods
  • Biomechanical Phenomena
  • Collagen / metabolism
  • Compressive Strength
  • Computer Simulation
  • Elasticity
  • Glycosaminoglycans / chemistry
  • Humans
  • Knee Joint
  • Menisci, Tibial / physiology*
  • Models, Biological
  • Models, Theoretical
  • Permeability
  • Stress, Mechanical
  • Viscosity

Substances

  • Glycosaminoglycans
  • Collagen