Risk-taking and fairness among cocaine-dependent patients in dual diagnoses: Schizophrenia and Anti-Social Personality Disorder

Sci Rep. 2020 Jun 22;10(1):10120. doi: 10.1038/s41598-020-66954-2.

Abstract

This study reports experimental results from a clinical sample of patients with a cocaine-related disorder and dual diagnosis: Schizophrenia and Anti-Social Personality Disorder. Both types of patients as well as a non-clinical group of students performed two incentivized decision-making tasks. In the first part of the experiment, they performed a lottery-choice task in order to elicit their degree of risk aversion. In the second part, they decided in two modified dictator games aimed at eliciting their aversion to advantageous and disadvantageous inequality. It is found that the Anti-Social Personality Disorder group exhibits no significant differences from the non-clinical sample in either task. However, compared with the students' sample, subjects from the group with schizophrenia show more risk aversion and exhibit more aversion towards disadvantageous inequality.

MeSH terms

  • Affect
  • Antisocial Personality Disorder / complications
  • Antisocial Personality Disorder / metabolism
  • Antisocial Personality Disorder / physiopathology
  • Cocaine / metabolism
  • Cocaine / pharmacology
  • Cocaine-Related Disorders / complications*
  • Cocaine-Related Disorders / physiopathology
  • Cocaine-Related Disorders / psychology*
  • Comorbidity
  • Decision Making
  • Diagnosis, Dual (Psychiatry) / psychology*
  • Female
  • Games, Experimental
  • Humans
  • Male
  • Personality Disorders
  • Risk-Taking
  • Schizophrenia / complications
  • Schizophrenia / metabolism
  • Schizophrenic Psychology
  • Social Behavior

Substances

  • Cocaine