This paper elucidates how the functionality of Patient-Reported Outcome (PRO) has evolved due to its digital transformation. Hence, PROs traditional use within healthcare is described and compared to the application of electronic PROs (ePROs); leading to a discussion regarding PROs functionality. The literature included in this paper stems from a systematic scoping review. The digitalization supplements former functionalities of PRO by enabling timely, accessible, systematical and progression oriented data; however, further improvements are necessary to enhance PROs application in current healthcare.
Keywords: PRO; Patient-reported outcome; digital mediation; ePRO and PROs functionality.