AUTOLOGOUS NEUROSENSORY RETINAL TRANSPLANT TO TREAT REFRACTORY SEROUS RETINAL DETACHMENT SECONDARY TO OPTIC DISK COLOBOMA

Retin Cases Brief Rep. 2022 Sep 1;16(5):606-609. doi: 10.1097/ICB.0000000000001031.

Abstract

Purpose: To describe a novel surgical technique to treat refractory serous retinal detachment in a patient with an optic disk coloboma.

Methods: Case report.

Results: A 32-year-old male patient with an optic disk coloboma in his right eye was referred for recurrent retinoschisis and serous macular detachment despite multiple vitrectomies. Previous surgical procedures included peeling of internal limiting membrane and juxtapapillary laser as well as different tamponade agents such as sulfur hexafluoride gas, standard silicone oil, and heavy silicone oil. Our first approach to close the cavity using autologous platelet concentrate and gas tamponade was also unsuccessful with early recurrence of the submacular fluid. In a second attempt, an autologous neurosensory retinal transplant was used to cover the optic disk cavity. At 17-month follow-up, the macula was still attached. As a postoperative complication, the patient developed high intraocular pressure, for which laser cycloablation eventually was necessary.

Conclusion: Autologous neurosensory retinal transplant may be a reasonable treatment option for patients with recurrent optic disk cavity-associated maculopathy.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Coloboma* / complications
  • Humans
  • Male
  • Optic Disk*
  • Optic Nerve / abnormalities
  • Retinal Detachment* / diagnosis
  • Retinal Detachment* / etiology
  • Retinal Detachment* / surgery
  • Tomography, Optical Coherence
  • Vitrectomy / methods

Supplementary concepts

  • Coloboma of optic nerve