Aquaporins in health and disease

Dimitrios E Magouliotis; Vasiliki S Tasiopoulou; Alexis A Svokos; Konstantina A Svokos

doi:10.1016/bs.acc.2020.02.005

Aquaporins in health and disease

Adv Clin Chem. 2020:98:149-171. doi: 10.1016/bs.acc.2020.02.005. Epub 2020 Mar 12.

Authors

Dimitrios E Magouliotis¹, Vasiliki S Tasiopoulou², Alexis A Svokos³, Konstantina A Svokos⁴

Affiliations

¹ Division of Surgery and Interventional Sciences, UCL, London, United Kingdom; Department of Surgery, University of Thessaly, Biopolis, Larissa, Greece. Electronic address: dimitrios.magouliotis.18@ucl.ac.uk.
² Department of Surgery, University of Thessaly, Biopolis, Larissa, Greece.
³ Geisinger Lewisburg-Women's Health, Lewisburg, PA, United States.
⁴ The Warren Alpert Medical School of Brown University, Providence, RI, United States.

PMID: 32564785
DOI: 10.1016/bs.acc.2020.02.005

Abstract

Aquaporins (AQPs) are transmembrane channel proteins that mainly facilitate the water translocation through the plasma cell membrane. For several years these proteins have been extensively examined for their biologic role in health and their potential implication in different diseases. Technological improvements associated with the methods employed to evaluate the functions of the AQPs have provided us with significant new knowledge. In this chapter, we will examine the role of AQPs in health and disease based on the latest currently available evidence.

Keywords: AQP; Aquaporin; Biomarker; Cancer; Disease; Health; Treatment.

Publication types

Review

MeSH terms

Animals
Aquaporins / metabolism*
Humans
Kidney Diseases / metabolism*
Neoplasms / metabolism*
Neurodegenerative Diseases / metabolism*
Respiratory Tract Diseases / metabolism*

Substances

Aquaporins