A rare cause of pneumoperitoneum due to clostridium perfringens in a cirrhotic patient

Acta Chir Belg. 2022 Jun;122(3):197-199. doi: 10.1080/00015458.2020.1785218. Epub 2020 Jul 1.

Abstract

Introduction: Abdominal gas gangrene caused by Clostridium perfringens is a rare differential diagnosis to pneumoperitoneum caused by bowel perforation. There are only a handful of case reports on this topic.

Patients and methods: We present the case of a 58 year old cirrhotic patient who represented to our ER after complicated surgery for retroperitoneal liposarcoma. On admission he complained of abdominal pain and mild fever. Due to leukocytosis and CRP a CT scan was performed which showed extensive free air. The patient was taken to the OR for suspected bowel perforation. No perforation could be identified after extensive search and lavage.

Results: Twelve hours after surgery microbiology reported extensive growth of clostridium perfringens in the cultures drawn from ascites. The patient was successfully treated with antibiotics and discharged home soon after.

Conclusion: Gas gangrene is a rare differential diagnosis to bowel perforation. Most reported cases are from cirrhotic patients. If no perforation can be identified in the OR postoperative antibiotics should cover clostridium perfringens.

Keywords: Clostridium perfringens; cirrhosis; gas gangrene; peritonitis; pneumoperitoneum.

Publication types

  • Case Reports

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Clostridium perfringens
  • Gas Gangrene* / diagnosis
  • Gas Gangrene* / etiology
  • Gas Gangrene* / therapy
  • Humans
  • Intestinal Perforation* / diagnosis
  • Intestinal Perforation* / etiology
  • Intestinal Perforation* / surgery
  • Liver Cirrhosis / complications
  • Liver Cirrhosis / drug therapy
  • Male
  • Middle Aged
  • Pneumoperitoneum* / complications

Substances

  • Anti-Bacterial Agents