Abstract
More and more studies are accumulating about COVID-19. Some aspects of the pathogenesis of the disease recall events occurring in Mg deficiency, such as a drop of T cells, increased plasma concentration of inflammatory cytokines, and endothelial dysfunction. We hypothesize that a low Mg status, which is rather common, might foment the transition from mild to critical clinical manifestations of the disease. Epidemiological, clinical, and fundamental research is needed to clarify the potential role of Mg deficiency in COVID-19.
Keywords:
COVID-19; inflammation; magnesium; pandemic.
MeSH terms
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Animals
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Betacoronavirus / pathogenicity*
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COVID-19
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Coronavirus Infections / blood*
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Coronavirus Infections / epidemiology
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Coronavirus Infections / immunology
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Coronavirus Infections / virology
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Disease Progression
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Host-Pathogen Interactions
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Humans
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Inflammation Mediators / blood
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Magnesium / blood*
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Magnesium Deficiency / blood*
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Magnesium Deficiency / epidemiology
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Magnesium Deficiency / immunology
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Magnesium Deficiency / virology
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Pandemics
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Pneumonia, Viral / blood*
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Pneumonia, Viral / epidemiology
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Pneumonia, Viral / immunology
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Pneumonia, Viral / virology
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Prognosis
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SARS-CoV-2
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T-Lymphocytes / immunology
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T-Lymphocytes / metabolism
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T-Lymphocytes / virology
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Time Factors
Substances
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Inflammation Mediators
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Magnesium