Protamine Induced Anaphylactic Shock after Peripheral Vascular Surgery

Ann Vasc Surg. 2020 Nov:69:450.e13-450.e15. doi: 10.1016/j.avsg.2020.06.016. Epub 2020 Jun 15.

Abstract

Anaphylactic reactions to protamine are quite rare and almost exclusively reported during cardiac surgery. In this report, we illustrate a rare case of protamine reaction after peripheral vascular surgery a couple of months after cardiac surgery and how the patient survived this critical complication.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Anaphylaxis / chemically induced*
  • Anaphylaxis / diagnosis
  • Anaphylaxis / physiopathology
  • Anaphylaxis / therapy
  • Cardiopulmonary Resuscitation
  • Coronary Artery Bypass*
  • Coronary Artery Disease / diagnostic imaging
  • Coronary Artery Disease / surgery*
  • Drug Hypersensitivity / diagnosis
  • Drug Hypersensitivity / etiology*
  • Drug Hypersensitivity / physiopathology
  • Drug Hypersensitivity / therapy
  • Extracorporeal Membrane Oxygenation
  • Heparin Antagonists / adverse effects*
  • Humans
  • Male
  • Peripheral Arterial Disease / diagnostic imaging
  • Peripheral Arterial Disease / surgery*
  • Protamines / adverse effects*
  • Treatment Outcome
  • Vascular Grafting*

Substances

  • Heparin Antagonists
  • Protamines