TNFα-Antagonist Use and Mucosal Inflammation Are Associated with Increased Intestinal Expression of SARS-CoV-2 Host Protease TMPRSS2 in Patients with Inflammatory Bowel Disease

Gastroenterology. 2021 Jun;160(7):2621-2622. doi: 10.1053/j.gastro.2020.05.091. Epub 2020 Jun 15.

Authors

Amber Bangma¹, Michiel D Voskuil¹, Rinse K Weersma²

Affiliations

¹ Department of Gastroenterology and Hepatology, University of Groningen, University Medical Centre Groningen and, Department of Genetics, University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands.
² Department of Gastroenterology and Hepatology, University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands.

No abstract available

Publication types

Letter
Comment

MeSH terms

COVID-19*
Humans
Inflammation
Inflammatory Bowel Diseases*
Peptide Hydrolases
Peptidyl-Dipeptidase A
SARS-CoV-2
Serine Endopeptidases
Tumor Necrosis Factor-alpha

Substances

Tumor Necrosis Factor-alpha
Peptide Hydrolases
Peptidyl-Dipeptidase A
Serine Endopeptidases
TMPRSS2 protein, human