Efficacy and safety of Jinhua Qinggan granules for coronavirus disease 2019 (COVID-19): A protocol of a systematic review and meta-analysis

Medicine (Baltimore). 2020 Jun 12;99(24):e20612. doi: 10.1097/MD.0000000000020612.

Abstract

Background: Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome (SARS)-COV2 and represents the causative agent of a potentially fatal disease. Jinhua Qinggan granules has definite effect in treating COVID-19 patients, but it has not been systematically evaluated for efficacy and safety.

Methods: Retrieved the database, including the China National Knowledge Infrastructure (CNKI), Chinese Biomedical literature Database (CBM), Chinese Scientific and Journal Database (VIP), Wan Fang database, PubMed, and EMBASE. Evaluate methodological quality and judge risk of bias through the Cochrane manual. RevMan 5.3 and STATA 16.0 software were used to perform the meta-analysis.

Results: This study will provide high-quality evidence of Jinhua Qinggan granules for COVID-19.

Conclusion: The conclusion of this study will provide evidence to determine whether Jinhua Qinggan granules is an effective treatment for COVID-19.

Prospero registration number: CRD42020182373.

MeSH terms

  • Betacoronavirus*
  • COVID-19
  • COVID-19 Drug Treatment
  • Coronavirus Infections / drug therapy*
  • Drugs, Chinese Herbal / adverse effects
  • Drugs, Chinese Herbal / therapeutic use*
  • Humans
  • Meta-Analysis as Topic
  • Pandemics
  • Pneumonia, Viral / drug therapy*
  • Randomized Controlled Trials as Topic
  • SARS-CoV-2
  • Systematic Reviews as Topic

Substances

  • Drugs, Chinese Herbal
  • jinhua qinggan granules