EFFICACY OF INTRAVITREAL AFLIBERCEPT INJECTIONS IN THE TREATMENT OF IDIOPATHIC RETINAL VASCULITIS, ANEURYSMS, AND NEURORETINITIS SYNDROME

Retin Cases Brief Rep. 2022 Jul 1;16(4):515-519. doi: 10.1097/ICB.0000000000001020.

Abstract

Purpose: To present a case of idiopathic retinal vasculitis, aneurysms, and neuroretinitis syndrome that was successfully managed with serial intravitreal aflibercept injections.

Methods: Ophthalmic imaging and visual acuity were used to monitor disease state and track treatment methods to determine the most valuable combination of treatment medication and treatment interval.

Results: A 28-year-old woman with idiopathic retinal vasculitis, aneurysms, and neuroretinitis syndrome status after panretinal photocoagulation of both eyes presented with bilateral cystoid macular edema. We demonstrate successful management of retinal cystoid macular edema associated with idiopathic retinal vasculitis, aneurysms, and neuroretinitis syndrome using serial intravitreal aflibercept injections.

Conclusion: Intravitreal aflibercept has a useful role in managing the potential retinal complications associated with idiopathic retinal vasculitis, aneurysms, and neuroretinitis syndrome and provides further insights into treatment of the later stages of this rare disease.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Aneurysm* / therapy
  • Angiogenesis Inhibitors / therapeutic use
  • Dementia
  • Female
  • Hearing Loss, Central
  • Humans
  • Intravitreal Injections
  • Macular Edema* / diagnosis
  • Macular Edema* / drug therapy
  • Macular Edema* / etiology
  • Optic Atrophy
  • Receptors, Vascular Endothelial Growth Factor
  • Recombinant Fusion Proteins
  • Retinal Vasculitis* / complications
  • Retinal Vasculitis* / diagnosis
  • Retinal Vasculitis* / drug therapy
  • Retinitis* / diagnosis
  • Retinitis* / drug therapy

Substances

  • Angiogenesis Inhibitors
  • Recombinant Fusion Proteins
  • aflibercept
  • Receptors, Vascular Endothelial Growth Factor

Supplementary concepts

  • Jensen syndrome