Obesity is the comorbidity more strongly associated for Covid-19 in Mexico. A case-control study

Obes Res Clin Pract. 2020 Jul-Aug;14(4):375-379. doi: 10.1016/j.orcp.2020.06.001. Epub 2020 Jun 12.

Abstract

Some comorbidities are associated with severe coronavirus disease (Covid-19) but it is unclear whether some increase susceptibility to Covid-19. In this case-control Mexican study we found that obesity represents the strongest predictor for Covid-19 followed by diabetes and hypertension in both sexes and chronic renal failure in females only. Active smoking was associated with decreased odds of Covid-19. These findings indicate that these comorbidities are not only associated with severity of disease but also predispose for getting Covid-19. Future research is needed to establish the mechanisms involved in each comorbidity and the apparent "protective" effect of cigarette smoking.

Keywords: COVID-19; Comorbidities; Obesity; Pandemic; Risk factor; SARS-CoV-2.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Betacoronavirus*
  • COVID-19
  • Case-Control Studies
  • Child
  • Child, Preschool
  • Comorbidity
  • Coronavirus Infections / epidemiology
  • Coronavirus Infections / etiology*
  • Female
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Mexico
  • Middle Aged
  • Obesity / complications*
  • Pandemics
  • Pneumonia, Viral / epidemiology
  • Pneumonia, Viral / etiology*
  • SARS-CoV-2
  • Young Adult