Genetics of Equine Orthopedic Disease

Vet Clin North Am Equine Pract. 2020 Aug;36(2):289-301. doi: 10.1016/j.cveq.2020.03.008. Epub 2020 Jun 11.

Abstract

Orthopedic diseases are a common cause for limited exercise capacity in the horse. They often underlie genetic risk factors, which can affect bone, articular cartilage, tendons, ligaments, and adnexal structures among others. The genetic effects can directly interfere with tissue development and skeletal growth or can trigger degenerative or inflammatory processes. Many of these diseases of the locomotor system like osteochondrosis are complex and can be affected by multifactorial influences. For this reason, it is important for those performing diagnostic procedures to have a comprehensive knowledge of orthopedic diseases, their prevalence within breeds, and genetic background.

Keywords: Genetic disposition; Horse; Orthopedics; Osteochondrosis.

Publication types

  • Review

MeSH terms

  • Animals
  • Cartilage, Articular / pathology
  • Horse Diseases / pathology
  • Horses
  • Musculoskeletal Diseases / genetics
  • Musculoskeletal Diseases / pathology
  • Musculoskeletal Diseases / veterinary*
  • Osteochondrosis / genetics
  • Osteochondrosis / veterinary