Cardiac injuries in coronavirus disease 2019 (COVID-19)

J Mol Cell Cardiol. 2020 Aug:145:25-29. doi: 10.1016/j.yjmcc.2020.06.002. Epub 2020 Jun 8.

Abstract

As the coronavirus disease 2019 (COVID-19) epidemic worsens, this global pandemic is impacting more than 200 countries/regions and more than 4,500,000 confirmed cases worldwide. COVID-19 is caused by the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), which might attack not only the respiratory system, but also the other important organs, including the heart. It was reported that COVID-19 patients with a past history of cardiovascular diseases would have a higher mortality. Meanwhile, elevated troponin levels were frequently observed in COVID-19 cases. Besides the comprehensive treatments for COVID-19, as a cardiologist, we should also remain vigilant about the cardiac injuries, especially those with severe emergent cardiovascular symptoms.

Keywords: COVID-19; Cardiovascular system; Injury; SARS-CoV-2.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Betacoronavirus*
  • Biomarkers / blood
  • COVID-19
  • Comorbidity
  • Coronary Disease / epidemiology*
  • Coronary Disease / virology
  • Coronavirus Infections / epidemiology*
  • Coronavirus Infections / immunology
  • Coronavirus Infections / mortality
  • Coronavirus Infections / virology
  • Humans
  • Interleukin-6 / blood
  • Male
  • Myocarditis / drug therapy
  • Myocarditis / epidemiology*
  • Myocarditis / immunology
  • Myocarditis / virology
  • Natriuretic Peptide, Brain / blood
  • Pandemics
  • Peptide Fragments / blood
  • Pneumonia, Viral / epidemiology*
  • Pneumonia, Viral / immunology
  • Pneumonia, Viral / mortality
  • Pneumonia, Viral / virology
  • Risk Factors
  • SARS-CoV-2
  • Treatment Outcome
  • Troponin I / blood

Substances

  • Biomarkers
  • IL6 protein, human
  • Interleukin-6
  • Peptide Fragments
  • Troponin I
  • pro-brain natriuretic peptide (1-76)
  • Natriuretic Peptide, Brain