G6PD deficiency shifts polarization of monocytes/macrophages towards a proinflammatory and profibrotic phenotype

Cell Mol Immunol. 2021 Mar;18(3):770-772. doi: 10.1038/s41423-020-0428-5. Epub 2020 Jun 10.

Authors

Rajesh Parsanathan¹, Sushil K Jain²

Affiliations

¹ Department of Pediatrics and Center for Cardiovascular Diseases and Sciences, Louisiana State University Health Sciences Center-Shreveport, 1501 Kings Highway, Shreveport, LA, 71130, USA.
² Department of Pediatrics and Center for Cardiovascular Diseases and Sciences, Louisiana State University Health Sciences Center-Shreveport, 1501 Kings Highway, Shreveport, LA, 71130, USA. sjain@lsuhsc.edu.

No abstract available

Publication types

Letter
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Fibrosis / etiology
Fibrosis / pathology*
Glucosephosphate Dehydrogenase Deficiency / complications*
Humans
Inflammation / etiology
Inflammation / pathology*
Macrophages / immunology*
Monocytes / immunology*
Phenotype*

Grants and funding

R01 AT007442/AT/NCCIH NIH HHS/United States