Extramammary Paget's Disease and Melanoma: 2 Cases of Double Cancers

Erika Lydrup; Jais Oliver Berg; Sofie Vetli Hjorth; Lisbet Rosenkrantz Hølmich; Jørgen Lock-Andersen; Annette Hougaard Chakera

doi:10.1159/000507917

Extramammary Paget's Disease and Melanoma: 2 Cases of Double Cancers

Case Rep Dermatol. 2020 May 18;12(2):107-113. doi: 10.1159/000507917. eCollection 2020 May-Aug.

Authors

Erika Lydrup¹, Jais Oliver Berg¹, Sofie Vetli Hjorth², Lisbet Rosenkrantz Hølmich¹, Jørgen Lock-Andersen¹, Annette Hougaard Chakera¹

Affiliations

¹ Department of Plastic Surgery, Herlev-Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.
² Department of Pathology, Herlev-Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.

Abstract

Extramammary Paget's disease (EMPD) is a rare intraepidermal neoplastic disease. There is a well-known relationship between EMPD and underlying malignancy. However, only a few cases of EMPD and cutaneous melanoma have been reported previously. In this case report we present 2 cases of such double cancers: one as a collision tumor, the other at separate sites. We discuss the pathogenesis, treatment, and importance of a thorough clinical and radiological examination and review the literature.

Keywords: Double cancer; Extramammary Paget's disease; Melanoma.

Publication types

Case Reports