Prevention of preeclampsia

Semin Fetal Neonatal Med. 2020 Oct;25(5):101123. doi: 10.1016/j.siny.2020.101123. Epub 2020 Jun 2.

Abstract

Preeclampsia is an obstetric disorder that affects 3-8% of pregnant women and remains a leading cause of short- and long-term neonatal and maternal morbidity and mortality. Professional societies recommend the use of low dose aspirin to prevent preeclampsia in high-risk women. However, interest in prevention of this disease and better understanding of its pathophysiology have led to growing research on other agents. This review focuses on the main therapeutic agents evaluated or in use for preeclampsia prevention.

Keywords: Aspirin; Esomeprazole; Metformin; Preeclampsia; Pregnancy; Statin.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Aspirin / therapeutic use*
  • Female
  • Fibrinolytic Agents / therapeutic use*
  • Humans
  • Hypertension / drug therapy
  • Hypertension / prevention & control
  • Pre-Eclampsia / drug therapy*
  • Pre-Eclampsia / physiopathology
  • Pre-Eclampsia / prevention & control*
  • Pregnancy

Substances

  • Fibrinolytic Agents
  • Aspirin