RETRACTED: New findings for dentin sialophosphoprotein studies: Applications of purified odontoblast-like cells derived from stem cells

J Oral Biosci. 2016 Nov;58(4):128-133. doi: 10.1016/j.job.2016.07.001. Epub 2016 Jul 13.

Abstract

This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal). This article has been retracted at the request of the Authors. After the retraction of the article [Hiyama T, Ozeki N, Mogi M, Yamaguchi H, Kawai R, Nakata K, Kondo A, Nakamura H. 2013. Matrix Metalloproteinase-3 in Odontoblastic Cells Derived from Ips Cells: Unique Proliferation Response as Odontoblastic Cells Derived from ES Cells. PLoS ONE 8(12): e83563. doi:10.1371/journal.pone.0083563] which contained fabricated/falsified data, the authors attempted to confirm original data for the results presented in their related publications. As a result, they reached a conclusion that there were no original data for the results presented in several their publications. This article was written on the basis of the seven publications retracted or to be retracted and it is no longer reliable. Reference 24: N. Ozeki, M. Mogi, R. Kawai, H. Yamaguchi, T. Hiyama, K. Nakata, H. Nakamura Mouse-induced pluripotent stem cells differentiate into odontoblast-like cells with induction of altered adhesive and migratory phenotype of integrin PLoS One, 8 (2013), p. e80026 Reference 25:R. Kawai, N. Ozeki, H. Yamaguchi, T. Tanaka, K. Nakata, M. Mogi, H. Nakamura Mouse ES cells have a potential to differentiate into odontoblast-like cells using hanging drop method Oral Dis, 20 (2014), pp. 395-403 Reference 26:N. Ozeki, M. Mogi, H. Yamaguchi, T. Hiyama, R. Kawai, N. Hase, K. Nakata, H. Nakamura, R.H. Kramer Differentiation of human skeletal muscle stem cells into odontoblasts is dependent on induction of alpha1 integrin expression J Biol Chem, 289 (2014), pp. 14380-14391 Reference 42:N. Ozeki, N. Hase, R. Kawai, H. Yamaguchi, T. Hiyama, A. Kondo, K. Nakata, M. Mogi Unique proliferation response in odontoblastic cells derived from human skeletal muscle stem cells by cytokine-induced matrix metalloproteinase-3 Exp Cell Res, 331 (2015), pp. 105-114 Reference 43: N. Ozeki, N. Hase, H. Yamaguchi, T. Hiyama, R. Kawai, A. Kondo, K. Nakata, M. Mogi Polyphosphate induces matrix metalloproteinase-3-mediated proliferation of odontoblast-like cells derived from induced pluripotent stem cells Exp Cell Res, 333 (2015), pp. 303-315 Reference 44: N. Ozeki, R. Kawai, N. Hase, T. Hiyama, H. Yamaguchi, A. Kondo, K. Nakata, M. Mogi Alpha2 integrin, extracellular matrix metalloproteinase inducer, and matrix metalloproteinase-3 act sequentially to induce differentiation of mouse embryonic stem cells into odontoblast-like Exp Cell Res, 331 (2015), pp. 21-37 Reference 45: N. Ozeki, M. Mogi, N. Hase, T. Hiyama, H. Yamaguchi, R. Kawai, A. Kondo, T. Matsumoto, K. Nakata Autophagy-related gene 5 and Wnt5 signaling pathway requires differentiation of embryonic stem cells into odontoblast-like cells Exp Cell Res, 341 (2016), pp. 92-104 All of the authors except Nobuaki Ozeki have agreed to retract the article. Nobuaki Ozeki, the corresponding author and the first author of the article, left Aichi Gakuin University in March 2018, and does not respond to co-authors inquiries. The authors deeply regret this error and any inconvenience it may have caused.

Publication types

  • Retraction of Publication
  • Retracted Publication