Endocrine Conditions and COVID-19

Skand Shekhar; Rachel Wurth; Crystal D C Kamilaris; Graeme Eisenhofer; Francisco J Barrera; Michelle Hajdenberg; Joselyne Tonleu; Janet E Hall; Ernesto L Schiffrin; Forbes Porter; Constantine A Stratakis; Fady Hannah-Shmouni

doi:10.1055/a-1172-1352

Endocrine Conditions and COVID-19

Horm Metab Res. 2020 Jul;52(7):471-484. doi: 10.1055/a-1172-1352. Epub 2020 Jun 8.

Authors

Affiliations

¹ Section on Endocrinology & Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health (NIH), Bethesda, Maryland, USA.
² Clinical Research Branch, National Institute of Environmental Health Sciences, NIH, North Carolina, USA.
³ Institute of Clinical Chemistry and Laboratory Medicine, and Department of Medicine III, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
⁴ Endocrinology Division, Internal Medicine Department, University Hospital "Dr. Jose E. Gonzalez", Universidad Autonoma de Nuevo Leon, Monterrey, Mexico.
⁵ Plataforma INVEST-KER Unit Mayo Clinic, School of Medicine, Universidad Autonoma de Nuevo Leon, Monterrey, Mexico.
⁶ College of Arts and Sciences at Washington University in St. Louis, Saint Louis, Missouri, USA.
⁷ Department of Medicine, Sir Mortimer B. Davis-Jewish General Hospital, McGill University, Montreal, Quebec, Canada.
⁸ Division of Translational Medicine, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, Maryland, USA.

Abstract

COVID-19 was declared a global pandemic by the WHO and has affected millions of patients around the world. COVID-19 disproportionately affects persons with endocrine conditions, thus putting them at an increased risk for severe disease. We discuss the mechanisms that place persons with endocrine conditions at an additional risk for severe COVID-19 and review the evidence. We also suggest precautions and management of endocrine conditions in the setting of global curfews being imposed and offer practical tips for uninterrupted endocrine care.

Publication types

Review

MeSH terms

COVID-19
Coronavirus Infections / complications*
Coronavirus Infections / epidemiology
Coronavirus Infections / therapy
Endocrine System Diseases / complications*
Endocrine System Diseases / epidemiology
Endocrine System Diseases / therapy
Humans
Pandemics
Pneumonia, Viral / complications*
Pneumonia, Viral / epidemiology
Pneumonia, Viral / therapy

Grants and funding

Funding Information This work was funded by the intramural research program of the National Institutes of Health.