More holes, more contrast? Comparing an 18-gauge non-fenestrated catheter with a 22-gauge fenestrated catheter for cardiac CT

PLoS One. 2020 Jun 8;15(6):e0234311. doi: 10.1371/journal.pone.0234311. eCollection 2020.

Abstract

Objective: To compare the performance of an 18-gauge nonfenestrated catheter (18-NFC) with a 22-gauge fenestrated catheter (22-FC) for cardiac CT angiography (CCTA) in patients with suspected coronary heart disease.

Subjects and methods: 74 consecutive patients imaged on a 2nd generation dual-source CT with arterial phase CCTA were included in this retrospective investigation to either an 18-NFC or 22-FC. In comparison to the 18-NFC, the 22-FC has three additional perforations for contrast agent dispersal proximal to the tip. We examined the two groups for differences in their average attenuation in the right and left ventricles (RV, LV) and in the atrium (RA, LA) as well as in the proximal right coronary artery (RCA) and the left main coronary artery (LM). The averages were calculated for both the 18-NFC and 22-FC.

Results: Catheters were successfully placed on the first attempt 97% (36/37) for 18-NFC and 95% (35/37) for the 22-FC. The following enhancement levels were measured: 22-FC (in Hounsfield-Units (HU)): RV = 203±29, LV = 523±36, RA = 198±29, LA = 519±38, RCA = 547±26, LM = 562±25; 18-NFC: RV = 146±26, LV = 464±32, RA = 141±24, LA = 438±35, RCA = 501±23, LM = 523±23; RV (p = 0,03), LV (p = 0.12), RA (p = 0.02), LA (p = 0.04), RCA (p = 0.3), LM (p = 0.33).

Conclusion: No significant differences in attenuation levels as well as in image quality of the coronary arteries were found between NFC and FC. Nevertheless, the 22-gauge FC examinations showed significantly higher attenuation in the left and right atrium as well as the right ventricle. Patients with poor venous access may benefit from a smaller gauge catheter that can deliver sufficiently high flow rates for CCTA.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Computed Tomography Angiography / instrumentation*
  • Contrast Media / administration & dosage
  • Coronary Angiography / instrumentation*
  • Coronary Disease / diagnostic imaging*
  • Equipment Design
  • Female
  • Humans
  • Male
  • Middle Aged
  • Retrospective Studies
  • Vascular Access Devices*
  • Young Adult

Substances

  • Contrast Media

Grants and funding

The Institute of Clinical Radiology and Nuclear Medicine has research agreements with Siemens Healthcare GmbH. JS receives institutional research support from Astellas, Bayer, and Siemens. JS has received consulting fees and/or speaker honoraria from Bayer, Elucid BioImaging, General Electric, Guerbet, HeartFlow Inc., and Siemens. The University Medical Center Groningen receives institutional research support from Siemens. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. The specific roles of these authors are articulated in the ‘author contributions’ section. The other authors have no conflict of interest to disclose.