Placental mesenchymal dysplasia in a normal female infant: a rare case report with follow-up

Yajing Sun; Jie Zheng; Zhongmin Jiang; Lidong Zhang; Shanshan Ding; Xiaozhi Liu

Placental mesenchymal dysplasia in a normal female infant: a rare case report with follow-up

Int J Clin Exp Pathol. 2020 May 1;13(5):896-900. eCollection 2020.

Authors

Yajing Sun¹, Jie Zheng¹, Zhongmin Jiang¹, Lidong Zhang¹, Shanshan Ding², Xiaozhi Liu³

Affiliations

¹ Department of Pathology, Tianjin Fifth Central Hospital 41 Zhejiang Road, Tanggu District, Tianjin, China.
² Department of Pathology, Chinese People's Liberation Army Rocket General Hospital 16 Xinjiekouwai Street, Xicheng District, Beijing, China.
³ Department of Central Laboratory, Tianjin Fifth Central Hospital 41 Zhejiang Road, Tanggu District, Tianjin, China.

PMID: 32509060
PMCID: PMC7270654

Abstract

Placental mesenchymal dysplasia (PMD) is a rare disorder of unknown etiology, which is often misdiagnosed as partial hydatidiform mole because of their similarity in ultrasonographic, gross, and histologic presentations. However, the treatment and prognosis of these two conditions are different. Patients with PMD often have intrauterine growth restriction, intrauterine fetal death, and Beckwith-Wiedemann syndrome, but there may also be a normal fetus. PMD with a normal female infant is extremely rare, and only a few cases have been reported. We report a case of PMD in a normal female infant and its follow-up results.

Keywords: P57; Placenta; hydatidiform mole; placental mesenchymal dysplasia (PMD).