Selective PPARα agonist pemafibrate inhibits TNF-α-induced S100A7 upregulation in keratinocytes

J Dermatol Sci. 2020 Jul;99(1):69-72. doi: 10.1016/j.jdermsci.2020.05.005. Epub 2020 May 19.

¹ Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
² Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan; Research and Clinical Center for Yusho and Dioxin, Kyushu University Hospital, Fukuoka, Japan.
³ Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan; Research and Clinical Center for Yusho and Dioxin, Kyushu University Hospital, Fukuoka, Japan; Division of Skin Surface Sensing, Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan. Electronic address: furue@dermatol.med.kyushu-u.ac.jp.

No abstract available

Publication types

(R)-2-(3-((benzoxazol-2-yl-d4 (3-(4-methoxyphenoxy-d7)propyl)amino)methyl)phenoxy) butanoic acid
Benzoxazoles
Butyrates
PPAR alpha
PPARA protein, human
S100 Calcium Binding Protein A7
S100A7 protein, human
TNF protein, human
Tumor Necrosis Factor-alpha