The prevalence of diabetic chronic kidney disease in adult Greek subjects with type 2 diabetes mellitus: A series from hospital-based diabetes clinics

Diabetes Res Clin Pract. 2020 Aug:166:108243. doi: 10.1016/j.diabres.2020.108243. Epub 2020 Jun 2.

Abstract

Aims: To examine the prevalence of diabetic chronic kidney disease (DCKD) and its risk factors in adult Greek subjects with type 2 diabetes mellitus (T2DM) in a population from hospital-based diabetes clinics.

Methods: This is a cross-sectional multicentre study based on data collected from Greek hospital-based diabetes clinics from June 2015 to March 2016. DCKD severity was defined according to the Kidney Disease: Improving Global Outcomes (KDIGO) 2012 guidelines. Multivariate analyses assessed the associations between DCKD and its potential risk factors.

Results: Among the entire population (n = 1759), the overall prevalence of DCKD was 45% including mild, moderate and severe CKD. Older age, male gender, body-mass index, lack of exercise and diabetes duration were significantly associated with DCKD.

Conclusions: In Greece, DCKD in T2DM is highly prevalent. It is significantly associated with demographic and lifestyle parameters, as well as T2DM complications, suggesting that further efforts to prevent DCKD should be addressed to subjects with specific characteristics.

Keywords: Complications; Diabetic chronic kidney disease; Microvascular; Nephropathy; Prevalence; Type 2 diabetes mellitus.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Cross-Sectional Studies
  • Diabetes Mellitus, Type 2 / complications
  • Diabetes Mellitus, Type 2 / epidemiology*
  • Diabetic Nephropathies / complications
  • Diabetic Nephropathies / epidemiology*
  • Diabetic Nephropathies / pathology
  • Female
  • Greece / epidemiology
  • Hemodialysis Units, Hospital / statistics & numerical data
  • Hospitals / statistics & numerical data
  • Humans
  • Male
  • Middle Aged
  • Prevalence
  • Renal Insufficiency, Chronic / complications
  • Renal Insufficiency, Chronic / epidemiology
  • Renal Insufficiency, Chronic / pathology
  • Risk Factors
  • Severity of Illness Index