End Products of Telomere Research

Roger R Reddel; Karen L MacKenzie; Tracy M Bryan

doi:10.1016/j.stem.2020.05.006

End Products of Telomere Research

Cell Stem Cell. 2020 Jun 4;26(6):804-805. doi: 10.1016/j.stem.2020.05.006.

Authors

Roger R Reddel¹, Karen L MacKenzie², Tracy M Bryan³

Affiliations

¹ Children's Medical Research Institute, Faculty of Medicine and Health, University of Sydney, Westmead, NSW 2145, Australia. Electronic address: rreddel@cmri.org.au.
² Children's Medical Research Institute, Faculty of Medicine and Health, University of Sydney, Westmead, NSW 2145, Australia; School of Women's and Children's Health, UNSW Sydney, Sydney, NSW 2052, Australia.
³ Children's Medical Research Institute, Faculty of Medicine and Health, University of Sydney, Westmead, NSW 2145, Australia.

PMID: 32502401
DOI: 10.1016/j.stem.2020.05.006

Abstract

Most rare inherited telomere biology disorders and some common aging-related diseases are associated with shortened telomeres. In this issue of Cell Stem Cell, insights into one of the rarest genetic causes of these disorders led to the discovery (Nagpal et al., 2020) of small molecules that lengthen telomeres.

Publication types

Comment

MeSH terms

Humans
Stem Cells / metabolism
Telomerase* / metabolism
Telomere Shortening
Telomere* / genetics
Telomere* / metabolism

Substances

Telomerase