Introduction: Epidural labor analgesia may decrease the risk of postpartum depression (PPD).
Methods: In a secondary analysis of a prospective study, the association between epidural utilization and PPD was evaluated using a Fisher's exact test. PPD was defined as an Edinburgh Postnatal Depression score of ≥ 10 at 6-8 weeks postpartum.
Results: 20% (13/65) of women meet criteria for PDD. 24% (n=12/50) of women who received epidural labor analgesia developed PPD, compared to 6.7% (n=1/15) of women who did not receive epidural labor analgesia (P = 0.27).
Conclusions: Labor epidural analgesia did not reduce the risk of postpartum depression.