Emerging Roles of PET/MR in the Pediatric Hospital

Sandra Saade-Lemus; Sara R Teixeira; Arastoo Vossough; Sabah Servaes; Lisa J States

doi:10.1016/j.cpet.2020.03.005

Emerging Roles of PET/MR in the Pediatric Hospital

PET Clin. 2020 Jul;15(3):253-269. doi: 10.1016/j.cpet.2020.03.005.

Authors

Sandra Saade-Lemus¹, Sara R Teixeira², Arastoo Vossough³, Sabah Servaes⁴, Lisa J States⁵

Affiliations

¹ Radiology Department, Children's Hospital of Philadelphia, 3401 Civic Center Boulevard, Philadelphia, PA 19104, USA; Section of Oncologic Imaging, Radiology Department, Children's Hospital of Philadelphia, 3401 Civic Center Boulevard, Philadelphia, PA 19104, USA.
² Radiology Department, Children's Hospital of Philadelphia, 3401 Civic Center Boulevard, Philadelphia, PA 19104, USA.
³ Radiology Department, Children's Hospital of Philadelphia, 3401 Civic Center Boulevard, Philadelphia, PA 19104, USA; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
⁴ Radiology Department, Children's Hospital of Philadelphia, 3401 Civic Center Boulevard, Philadelphia, PA 19104, USA; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA; Section of Oncologic Imaging, Radiology Department, Children's Hospital of Philadelphia, 3401 Civic Center Boulevard, Philadelphia, PA 19104, USA.
⁵ Radiology Department, Children's Hospital of Philadelphia, 3401 Civic Center Boulevard, Philadelphia, PA 19104, USA; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA; Section of Oncologic Imaging, Radiology Department, Children's Hospital of Philadelphia, 3401 Civic Center Boulevard, Philadelphia, PA 19104, USA. Electronic address: states@email.chop.edu.

PMID: 32498981
DOI: 10.1016/j.cpet.2020.03.005

Abstract

Add "improving" before "detection"? PET/MR is beneficial particularly in pediatric patients who undergo recurrent imaging, such as those with cancer or chronic inflammatory disease. PET/MR has advantages compared with PET/computed tomography, including decreased radiation exposure and superior characterization of soft tissue. Ongoing challenges include reducing examination duration and costs and detection of pulmonary lesions. Accepted clinical applications of PET/MR in pediatric patients are evaluation of epileptic foci and diagnosis, staging, and follow-up of solid tumors. PET/MR also may have a role in diagnosis and management of infectious and inflammatory conditions relevant to the pediatric population, including osteomyelitis and Crohn disease.

Keywords: Oncology; PET/MR imaging; Pediatrics; Radiation dose.

Publication types

Review

MeSH terms

Brain Neoplasms / diagnostic imaging*
Child
Epilepsy / diagnostic imaging*
Hospitals, Pediatric
Humans
Magnetic Resonance Imaging / methods*
Multimodal Imaging / methods*
Positron-Emission Tomography / methods*