Four pediatric cases of secondary neoplasms arising in nevus sebaceous

Lei Jiao; Xiaofeng Han; Jiaosheng Xu; Juan Sun; Lin Ma

doi:10.1111/dth.13762

Four pediatric cases of secondary neoplasms arising in nevus sebaceous

Dermatol Ther. 2020 Nov;33(6):e13762. doi: 10.1111/dth.13762. Epub 2020 Jul 8.

Authors

Lei Jiao¹, Xiaofeng Han¹, Jiaosheng Xu¹, Juan Sun¹, Lin Ma¹

Affiliation

¹ Department of Dermatology, Beijing Children's Hospital, Capital Medical University, National Center For Children's Health, Beijing, China.

PMID: 32495466
DOI: 10.1111/dth.13762

Abstract

Secondary neoplasms of epidermal adnexal origin have been reported to develop into nevus sebaceous (NS), mainly in adulthood but rarely in children. Four cases of secondary neoplasms were identified in 413 children of nevus sebaceous from 2015 to 2019 by our department, accounting for 1% of all cases. We here report the clinical, dermoscopical, and histopathological features of these tumors, including syringocystadenoma papilliferum (SCAP), pilomatricoma, trichilemmoma, and basal cell carcinoma (BCC). We recommend prophylactic excision of nevus sebaceous before puberty, not only because of the cosmetical disfigurement but also due to the risk of malignant transformation.

Keywords: children; nevus sebaceous; secondary neoplasms.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Carcinoma, Basal Cell*
Child
Humans
Neoplasms, Second Primary*
Nevus*
Nevus, Sebaceous of Jadassohn*
Skin Neoplasms*

Abstract

Publication types

MeSH terms

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