Candida Infective Endocarditis During the Infectious Diseases and Substance Use Disorder Syndemic: A Six-Year Case Series

N P Sankar; K Thakarar; Kristina E Rokas

doi:10.1093/ofid/ofaa142

Candida Infective Endocarditis During the Infectious Diseases and Substance Use Disorder Syndemic: A Six-Year Case Series

Open Forum Infect Dis. 2020 Apr 25;7(5):ofaa142. doi: 10.1093/ofid/ofaa142. eCollection 2020 May.

Authors

N P Sankar¹, K Thakarar^{2

3}, Kristina E Rokas⁴

Affiliations

¹ University of New England College of Osteopathic Medicine, Biddeford, Maine, USA.
² Center for Outcomes Research and Evaluation, Maine Medical Center Research Institute, Portland, Maine, USA.
³ Division of Infectious Diseases, Maine Medical Center, Portland, Maine, USA.
⁴ Department of Pharmacy Maine Medical Center, Portland, Maine, USA.

Abstract

Treatment for Candida infective endocarditis (IE) has not been extensively studied in the setting of rising injection drug use. There were 12 cases of Candida IE at the Maine Medical Center between 2013 and 2018. The patient characteristics, treatment regimens, and outcomes were retrospectively analyzed.

Keywords: Candida; amphotericin B; echinocandins; endocarditis; injection drug use (IDU).