CPK-MB

Excerpt

Creatine kinase (CK) is a dimeric enzyme that catalyzes the reversible phosphorylation of creatine by ATP. In 1966 creatine kinase isoenzymes were identified in various tissues. The isoenzymes of CK are dimers of either type B or type M polypeptide chains, BB isoenzymes are found in the central nervous system, and MM isoenzyme is a principal component in adult skeletal muscles. The myocardium has 15% CK-MB isoenzyme and 85% CK-MM. Skeletal muscles contain about 1% to 3% of CK-MB.