Histology, Howell Jolly Bodies

Excerpt

Howell-Jolly bodies are nuclear remnants found in red blood cells (erythrocytes) under various pathological states. They are most commonly present in patients with absent or impaired function of the spleen; this is because one of the spleen’s functions is to filter deranged blood cells and remove the intracellular inclusions left by the erythrocyte precursors (see Image. Howell–Jolly Body). William Howell and Justin Jolly in the early 1900s first discovered Howell-Jolly bodies in the early 1900s.