Improved diagnostic policy for respiratory tract infections essential for patient management in the emergency department

Future Microbiol. 2020 May;15(8):623-632. doi: 10.2217/fmb-2019-0119. Epub 2020 Jun 3.

Abstract

Aim: Establishing an optimal diagnostic policy for patients with respiratory tract infections, at the emergency department (ED) of a university hospital in The Netherlands. Methods: Adult patients were sampled at admission, during the respiratory season (2014-2015). The FilmArray-RP was implemented at the clinical virology laboratory. Diagnostics were provided from 8 am to 10 pm, weekends included. Results: 436/492 (89%) results were available while patients were still at the ED. Median TAT from admission to test result was 165 min (IQR: 138-214). No antibiotics were prescribed in 94/207 (45%) patients who tested positive for a virus. 185/330 (56%) hospitalized patients did not need admission with isolation measures. The value-based measure, expressed in euro-hour (€h), increased to tenfold compared with previous policy. Conclusion: An optimal policy is essential for patient management, by providing timely, reliable diagnostics.

Keywords: clinical virology; co-creation; diagnostic stewardship; emergency department; patient management; point-of-care testing; respiratory tract infections.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Anti-Bacterial Agents / therapeutic use
  • Emergency Service, Hospital / statistics & numerical data
  • Female
  • Health Policy
  • Hospitalization
  • Humans
  • Male
  • Middle Aged
  • Respiratory Tract Infections / diagnosis*
  • Respiratory Tract Infections / drug therapy
  • Young Adult

Substances

  • Anti-Bacterial Agents