Dataset of voxelwise correlated signal values of ADC, rCBV and FAP-specific PET of 13 Glioblastoma patients

Manuel Röhrich; Lisa Loi; Ralf Floca; Uwe Haberkorn; Daniel Paech

doi:10.1016/j.dib.2020.105712

Dataset of voxelwise correlated signal values of ADC, rCBV and FAP-specific PET of 13 Glioblastoma patients

Data Brief. 2020 May 15:31:105712. doi: 10.1016/j.dib.2020.105712. eCollection 2020 Aug.

Authors

Manuel Röhrich^{1

2}, Lisa Loi³, Ralf Floca^{4

5}, Uwe Haberkorn^{1

2

6}, Daniel Paech³

Affiliations

¹ Clinical Cooperation Unit Nuclear Medicine, German Cancer Research Center (DKFZ), Heidelberg, Germany.
² Department of Nuclear Medicine, University Hospital Heidelberg, Germany.
³ Division of Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
⁴ Division of Medical Image Computing, German Cancer Research Center (DKFZ), Heidelberg, Germany.
⁵ Department of Radiation Oncology, University Hospital Heidelberg, Germany.
⁶ Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany.

Abstract

This dataset is based on multimodal MRI and FAP-specific PET/CT Imaging applied to 13 patients with histologically proven glioblastomas. Imaging Data was processed using Medical Imaging Interaction Toolkit (MITK) software. MRI images (contrast enhanced T1w, T2w/FLAIR, ADC, rCBV) were co-registrated with FAP-specific PET images. T2w/FLAIR hyperintensities and contrast enhancing lesions were segmented manually. Necrotic areas were segmented manually and subtracted from T2w/FLAIR hyperintensities and contrast enhancing lesions. Voxelwise ADC/rCBV and PET signal intensities in projection on T2w/FLAIR hyperintensities and contrast enhancing lesions were extracted using the pixel dumper function of the MITK software and stored as excel-files. The data presented in this article has been analysed and described in the article FAP-specific "PET signaling shows a moderately positive correlation with relative CBV and no correlation with ADC in 13 IDH wildtype Glioblastomas" published in the European Journal of Radiology.

Keywords: ADC; CBV; FAP; Fibroblast Activation Protein; Glioblastoma; PET.