Symptomatic Intraosseous Vascular Malformation of Infraorbital Rim: A Case Report With Literature Survey

Anticancer Res. 2020 Jun;40(6):3333-3343. doi: 10.21873/anticanres.14316.

Abstract

Background/aim: Intraosseous orbital hemangiomas or vascular malformations (VM) are rare. This report is intended to complement the experience of diagnosing and treating a rare vascular lesion at this site. Special attention is paid to three-dimensional imaging and the morphological distinction between the two entities in this location.

Case report: A 54-year-old female was examined and surgically treated for an exophytic firm mass of the infraorbital, which had become palpable as a hard mass due to growth in size. At first, a bone tumor, for example, an osteoma, was suspected. Intraoperatively, an osseous expansion with distinct fenestrations of the newly grown bone's surface, was detected. The lesion was firmly attaching to the orbital rim. The densely vascularized tumor was well defined to the soft tissues but had grown in continuity from the orbital floor and rim. Vascularized cavities caused the tumor to have a slightly reddish color. The histological examination confirmed the suspicion of the lesion's vascular origin. The lesion's immunohistochemical expression profile approved the final diagnosis of intraosseous VM.

Conclusion: The symptoms of intraosseous vascular lesions of the orbit are determined by location and size. Modern imaging techniques facilitate the estimation of tumor-like expansion of lesions. However, the imaging characteristics of intraosseous vascular lesions are very variable. The symptoms of the patient presented herein show that growth phases of a vascular orbital malformation can occur in later stages of life and are initially indistinguishable from a neoplasm. In individual cases, patient care necessitates advanced diagnostic measures to establish the diagnosis and determine surgical therapy.

Keywords: 3D reconstruction; Vascular malformation; bone mineral density; cone beam computed tomography; differential diagnosis; haemangioma; immunohistochemistry; intraosseous; orbit.

Publication types

  • Case Reports

MeSH terms

  • Female
  • Humans
  • Immunohistochemistry
  • Middle Aged
  • Orbital Neoplasms / blood supply*
  • Orbital Neoplasms / pathology
  • Vascular Malformations / etiology*