Marine Biocompounds for Neuroprotection-A Review

Mar Drugs. 2020 May 31;18(6):290. doi: 10.3390/md18060290.

Abstract

While terrestrial organisms are the primary source of natural products, recent years have witnessed a considerable shift towards marine-sourced biocompounds. They have achieved a great scientific interest due to the plethora of compounds with structural and chemical properties generally not found in terrestrial products, exhibiting significant bioactivity ten times higher than terrestrial-sourced molecules. In addition to the antioxidant, anti-thrombotic, anti-coagulant, anti-inflammatory, anti-proliferative, anti-hypertensive, anti-diabetic, and cardio-protection properties, marine-sourced biocompounds have been investigated for their neuroprotective potential. Thus, this review aims to describe the recent findings regarding the neuroprotective effects of the significant marine-sourced biocompounds.

Keywords: Alzheimer’s disease; Parkinson’s disease; marine biocompounds; neurodegeneration; neuroprotection.

Publication types

  • Review

MeSH terms

  • Animals
  • Aquatic Organisms*
  • Humans
  • Neuroprotective Agents / therapeutic use*

Substances

  • Neuroprotective Agents